Infiniti has determined that some 2000-2001 model year Infiniti Q45 vehicles may have a defect which relates to motor vehicle safety. The alloy wheels used on these vehicles may have a casting defect that could cause cracks to develop as the vehicle is being driven. If a sufficient number of cracks develop, the wheel could fail and separate from the mounting hub, resulting in loss of control and a crash. The spare tire steel wheel is not affected.